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Omega-3s in Dry Eye: Essential Insights

The Role of Omega-3 Fatty Acids in Dry Eye Treatment: What You Need to Know

Dry eye syndrome is a common condition that affects people of all ages. Whether it's due to long hours in front of screens, environmental factors, or underlying health issues, the discomfort of dry eyes can be a persistent challenge. While traditional treatments like artificial tears and prescription medications often help, there's also been a lot of discussion around the role of diet, particularly omega-3 fatty acids, in managing and even preventing dry eye. Let’s explore what you need to know about this topic.





The Importance of Omega-3s in Your Diet

Omega-3 fatty acids (O3FAs) are essential for many bodily functions, including eye health. They include alpha-linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). These nutrients are crucial for reducing inflammation, which is a significant factor in dry eye syndrome. On the other hand, omega-6 fatty acids (O6FAs), commonly found in the Western diet, tend to promote inflammation when consumed in excess.


Ideally, our diets should have a balanced ratio of omega-6 to omega-3, but most people consume far more omega-6 than omega-3, creating an inflammatory environment in the body. To help manage dry eye symptoms, it's important to include omega-3-rich foods in your diet. These can be found in fish like salmon and sardines, flaxseed oil, walnuts, and certain fortified foods like eggs and yogurt. If you’re not getting enough omega-3s from your diet, a supplement might be recommended.



How Omega-3s Can Help with Dry Eye

Research suggests that omega-3s can play a beneficial role in managing dry eye. They work by reducing inflammation in the glands that produce the oily layer of your tears, which helps prevent them from evaporating too quickly. Some studies have shown that people who consume more omega-3s have better tear quality and fewer dry eye symptoms.


However, there has been some controversy in recent years. A major study known as the DREAM study concluded that omega-3 supplements didn’t provide more relief than a placebo. But it’s important to note that the placebo in this study was olive oil, which itself has anti-inflammatory properties. This has led to some debate about the study's conclusions, and many experts still believe that omega-3s can be a helpful part of a comprehensive dry eye treatment plan.


What This Means for You

If you’re struggling with dry eyes, incorporating omega-3s into your diet or taking a supplement could be highly beneficial. In our clinic, we believe in a personalized approach, starting with a blood test to measure your Omega-3 Index. This simple finger prick test, done right in the office, helps us determine the exact amount of EPA/DHA you need. We repeat the test every 3-6 months, depending on your initial results, to monitor your progress and make adjustments as needed.


I typically recommend starting with a daily dose of at least 1,000mg of EPA/DHA. It’s important to keep in mind that the effects of omega-3s on dry eye symptoms may take a few months to become noticeable, so patience is key.


Choosing the right type of omega-3 supplement is also crucial. Lower-quality supplements, often in ethyl ester form, can sometimes cause a fishy aftertaste or mild digestive issues. However, when you use a doctor-recommended triglyceride-based supplement, these adverse effects are usually minimal. If you’re on medications for blood thinning or other conditions, we’ll need to discuss how omega-3s might interact with them to ensure your safety.


PRN Omega-3 Supplements
Courtesy of Physician Recommended Neutriceuticals (PRN)

The Bottom Line

Omega-3 fatty acids are just one piece of the puzzle in managing dry eye syndrome. While there’s some debate over their effectiveness, many patients find that they do help improve their symptoms. If you’re interested in trying omega-3s as part of your dry eye treatment, let’s talk about the best way to incorporate them into your overall care plan.

Remember, your eye health is a partnership, and I’m here to help you find the most effective and comfortable solutions for your needs.


In good health,








  1. Hussain M, Shtein RM, Pistilli M, Maguire MG, Oydanich M, Asbell PA; DREAM Study Research Group. The Dry Eye Assessment and Management (DREAM) extension study - A randomized clinical trial of withdrawal of supplementation with omega-3 fatty acid in patients with dry eye disease. Ocul Surf. 2020 Jan;18(1):47-55. doi: 10.1016/j.jtos.2019.08.002. Epub 2019 Aug 16. PMID: 31425752; PMCID: PMC7004875.

  2. The PRN Advantage. (n.d.). https://prnvision.com/the-prn-advantage/

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